Buy TB-500 10mg: Synthetic Thymosin Beta-4 Fragment for Tissue Repair Research

TB-500 (10mg) is a synthetic peptide fragment derived from Thymosin Beta-4 (Ac-LKKTETQ), widely used in laboratory research to investigate tissue repair and regenerative processes. Studies explore its ability to promote cell migration, stimulate angiogenesis, enhance actin polymerization, and reduce inflammation, making it a valuable tool for research into wound healing, musculoskeletal recovery, tendon/ligament repair, cardiac tissue protection, and other regenerative models.

Amino Acid Sequence: Ac-Lys-Lys-Thr-Glu-Thr-Gln (Ac-LKKTETQ) Molecular Formula: C38H68N14O14 Molecular Weight: 889.0 g/mol Purity: ≥99% (lyophilized, research-grade)

Important Notice: This peptide is strictly intended for research and laboratory use only. Not for human consumption, diagnostic, therapeutic, or veterinary purposes. Please review and agree to our Terms and Conditions before ordering.

What is TB-500?

TB-500 is the active, N-terminally acetylated fragment (amino acids 17–23) of the naturally occurring 43-amino-acid protein Thymosin Beta-4 (TB4). Thymosin Beta-4 is one of the most abundant actin-sequestering proteins in cells, and its synthetic fragment retains key biological activities while offering improved stability and research handling.

In experimental settings, TB-500 is studied for its role in upregulating actin sequestration, facilitating cytoskeletal reorganization, and supporting cellular repair mechanisms across various tissue types.

Mechanism of Action in Research

TB-500 is investigated for:

• Promoting cell migration (chemotaxis) of endothelial cells, fibroblasts, and keratinocytes
• Stimulating angiogenesis via VEGF pathway upregulation and new vessel formation
• Enhancing actin polymerization and cytoskeletal dynamics for cell motility and structure
• Reducing inflammation by modulating pro-inflammatory cytokines and NF-κB signaling
• Supporting extracellular matrix remodeling and tissue regeneration

These properties position TB-500 as a key compound in models of acute injury, chronic wounds, musculoskeletal damage, and ischemic tissue repair.

Key Research Areas and Potential Insights

TB-500 continues to attract attention in regenerative medicine, orthopedics, and wound healing research.

Wound Healing and Skin Repair

Studies examine accelerated closure of cutaneous wounds, reduced scar formation, and improved re-epithelialization in animal models.

Musculoskeletal Recovery

Research focuses on tendon, ligament, muscle, and cartilage repair, including protection against fibrosis and enhancement of structural recovery post-injury.

Angiogenesis and Vascular Repair

Investigations explore new blood vessel formation in ischemic or damaged tissues, with implications for cardiac and peripheral vascular models.

Anti-Inflammatory and Protective Effects

Additional work assesses reductions in inflammatory markers, protection against oxidative stress, and potential benefits in models of cardiac ischemia or neurodegeneration.

Research Applications

The 10mg vial supports:

• In-vitro migration, tube formation, and actin-binding assays
• Preclinical models of wound healing, tendon/ligament injury, muscle strain, and cardiac ischemia
• Angiogenesis, inflammation, and tissue remodeling studies
• Dose-response, pharmacokinetics, and combination peptide experiments

Reconstitution typically uses bacteriostatic water for precise dosing in lab protocols.

Why Choose 99% Pure TB-500 10mg?

Our TB-500 delivers ≥99% purity for consistent, reproducible results in cell motility assays, angiogenesis models, and regenerative endpoint measurements. Third-party tested and lyophilized for maximum stability.

In summary, TB-500 10mg is a high-quality synthetic Thymosin Beta-4 fragment for advanced research into tissue repair, wound healing, musculoskeletal recovery, angiogenesis, cell migration, actin dynamics, and inflammation modulation. Elevate your regenerative and injury-repair studies with this potent research peptide.

Latest Testing:Link to Report