Buy SS-31 50mg: Mitochondria-Targeted Peptide for Advanced Cellular Research

SS-31 50mg (also known as Elamipretide, Bendavia, or MTP-131) is a synthetic mitochondria-targeted tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂) widely researched for optimizing mitochondrial function, reducing oxidative stress, and enhancing cellular bioenergetics. This high-capacity 50mg vial supports extensive investigations into ATP production, ROS scavenging, cardiolipin stabilization, age-related mitochondrial decline, neuroprotection, cardiovascular protection, kidney function models, ischemia-reperfusion injury, and regenerative processes in experimental systems.

Peptide Sequence: D-Arg-2′,6′-dimethylTyr-Lys-Phe-NH₂ Molecular Formula: C32H49N9O5 Molecular Weight: 639.8 g/mol Purity: ≥99% (lyophilized, research-grade)

Important Notice: This peptide is strictly intended for research and laboratory use only. Not for human consumption, diagnostic, therapeutic, or veterinary purposes. Please review and agree to our Terms and Conditions before ordering.

What is SS-31?

SS-31 is a small, cell-permeable cationic tetrapeptide engineered to selectively accumulate in the inner mitochondrial membrane by binding with high affinity to cardiolipin. This interaction stabilizes mitochondrial cristae architecture, optimizes electron transport chain supercomplexes, shifts cytochrome c from peroxidase to electron carrier function, and reduces reactive oxygen species (ROS) leakage.

In preclinical models, SS-31 rapidly improves mitochondrial energetics, restores ADP sensitivity via adenine nucleotide translocator (ANT) modulation, enhances oxidative phosphorylation efficiency, and supports physiological performance without altering mitochondrial content in healthy states.

The larger 50mg format is ideal for high-volume experiments, long-term studies, bulk reconstitution, or multi-protocol research.

Mechanism of Action in Research

SS-31 is studied for:

• High-affinity binding to cardiolipin to preserve membrane structure and ETC organization
• Scavenging mitochondrial ROS and mitigating oxidative damage
• Increasing ATP synthesis and improving bioenergetic efficiency
• Enhancing ADP uptake and sensitivity through ANT interaction
• Inhibiting mitochondrial permeability transition pore opening and apoptosis
• Modulating inflammation, senescence, and redox homeostasis in stressed or aged cells

These targeted effects enable rapid functional rescue in dysfunctional mitochondria across diverse tissues.

Key Research Findings and Benefits

SS-31 shows broad applicability in mitochondrial biology and disease models.

Mitochondrial Energetics & Aging

Research demonstrates reversal of age-related declines in ATP production, redox balance, and exercise capacity in skeletal muscle, heart, kidney, and brain models.

Neuroprotection & Brain Health

Studies explore protection against ischemia, traumatic injury, and age-related cognitive decline via mitochondrial stabilization and ROS reduction.

Cardiovascular & Organ Protection

Investigations highlight benefits in heart failure analogs, ischemia-reperfusion injury, renal dysfunction, and glomerular preservation in advanced age.

Broader Regenerative & Disease Models

Additional work assesses roles in Barth syndrome analogs, Friedreich ataxia models, chronic fatigue analogs, dry AMD, and other mitochondrial-linked conditions.

Research Applications

The 50mg vial supports:

• Extensive mitochondrial bioenergetics, ROS, and ATP assays
• Long-term aging, neurodegeneration, ischemia, and metabolic disorder models
• Redox profiling, histomorphometry, and functional recovery studies
• Dose-response, pharmacokinetics, chronic dosing, and high-volume experiments

Reconstitution typically uses bacteriostatic water for precise concentrations in lab protocols.

Why Choose 99% Pure SS-31 50mg?

Our SS-31 delivers ≥99% purity for consistent, reproducible results in mitochondrial signaling, oxidative stress assays, and bioenergetic endpoint measurements. Third-party tested and lyophilized for superior stability.

In summary, SS-31 50mg is a premium mitochondria-targeted tetrapeptide for pioneering research into mitochondrial optimization, oxidative stress reduction, ATP enhancement, aging reversal, neuroprotection, and organ-specific mitochondrial rescue. Elevate your cellular energy, longevity, and disease-model studies with this high-capacity research tool.

Latest Testing: Link to Report